Drugs that Cause Depression

Sad Depressed Lady

Medical studies have continually found out that some drugs prescribed by physicians can alter your moods and make you feel depressed. Moreover, as you age, your body undergoes some biological changes that put you at greater risk of suffering from depression when you take certain drugs. Luckily, most doctors can reconsider the prescription.

if you inform them that you are experiencing symptoms that are typical characteristics of depression. These symptoms include sadness, excessive fatigue, restlessness, lack of energy and despair.

In such instances, these doctors opt to layer these drugs with a new drug such as antidepressants. These new drugs may possibly trigger other side effects. The drugs listed below have been linked to depression in some patients, especially the elderly.


They are a group of central nervous system depressants that work by slowing down brain function, according to Elmhurst College. They are normally prescribed for preventing epileptic seizures and to treat anxiety. However, these drugs are prone to abuse. Common examples include the Secobarbital and Phenobarbital.

Beta-Adrenergic Blockers

They are also known as beta-blockers. These drugs are commonly used in to treat various heart complications such as heart failure, hypertension and certain unusual heart rhythms. These drugs work by obstructing the effect of adrenaline, thus reducing the heart rate. Beta-blockers may also be used to treat migraine headaches, tremors, angina and certain kinds of glaucoma. These drugs have some adverse effects such as fatigue and sexual dysfunction. Examples of beta-blockers include Atenolol, Carvedilol and Lopressor.


These types of drugs are prescribed to treat insomnia, for muscle relaxation and to treat anxiety, since they function as central nervous system depressants. Withdrawal from benzodiazepines triggers depression. Some common benzodiazepines include Xanax, ProSom, Dalmane, Klonopin, Librium, Halcion, Ativan and Valium. These drugs can accumulate in your body to toxic levels if they aren’t fully metabolized by the liver.


Corticosteroids are prescribed to treat lupus, gout, rheumatoid arthritis, Sjougren’s syndrome and inflammation of the blood vessels. Corticosteroids lower the serotonin levels in the body, causing depression and other psychiatric disorders. Moreover, depression can also be a side effect of corticosteroids withdrawal. Some common corticosteroids include Prednisone, Cortisone and Triamcinolone. Recommended alternatives to corticosteroids are Ultram, Vicodin and Tylenol.

Bromocriptine (Parlodel)

This drug is prescribed to treat Parkinson’s disease by regulating the levels of dopamine, which is the neurotransmitter that controls reward and pleasure centers in the brain. High levels of dopamine have been linked to depression. The most commonly prescribed Parkinson’s medication is the Levodopa, which is converted into dopamine once it reaches the brain. The drug is normally combined with Carbidopa to prevent it from disintegrating before reaching the brain. Examples include Stalevo, Atamet and Sinemet.


These drugs are used to control epileptic seizures and to treat other medical conditions such as bipolar disorder, mania and neuropathic pain. Anticonvulsants act on the neurotransmitters, which act as the chemical transmitters in the brain. They work by blocking the flow of signals from the central nervous system (CNS) thus limiting the seizures from spreading. Examples of anticonvulsants include Zarontin,Neurontin and Celontin.


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