Treat Depression with MAOI Medication

depressed couch potato

Depression is more than just feeling sad or blue every once in a while. Depression is a common, life-long condition that affects a person’s thoughts, feelings, moods, behavior and physical health.

In fact, according to the National Alliance of Mental Illness, more than 25 million adults are affected by depression each year.

It is important that people with depression obtain an accurate diagnosis and receive proper treatment in order to keep symptoms from returning.

How Is Depression Treated?

Treatment for depression may include one or more antidepressant medications and/or psychotherapy. A treatment plan should be devised with close cooperation between a patient and his or her doctor.

What Are Antidepressants?

Antidepressants are prescription medications that work on chemicals in the brain called neurotransmitters. Serotonin and norepinephrine are the two neurotransmitters that are targeted by antidepressants because they have been found to help regulate a person’s mood.

There are several different classes of antidepressant medications that may be used to treat depression. These include selective serotonin re-uptake inhibitors (SSRIs), serotonin and norepinephrine re-uptake inhibitors (SNRIs), monoamine oxidase inhibitors (MAOIs) and tricyclics.

What Are MAOIs?

MAOIs – monoamine oxidase inhibitors – are not commonly prescribed today as they have several food and medication interactions, which require adherence to a strict diet. Furthermore, MAOIs cannot be used in combination with SSRIs.

MAOIs may be effective in people who do not respond to other antidepressant medications or those who have atypical depression and are affected with anxiety, excessive sleeping, or irritability as well.

Medications found in the MAOI class include Nardil (phenelzine), Marplan (isocarboxazid), Parnate (tranyclcypromine sulfate) and Emsan patch (selegiline).

Source: National Alliance on Mental Illness


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