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Clozapine (Clozaril)

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Clozapine is an oral medication prescribed to treat the symptoms of schizophrenia. Schizophrenia is a mental illness that causes disturbed or unusual thinking, loss of interest in life or apathy, and strong, often inappropriate emotions. It is sometimes used off label to treat bipolar disorder. Clozapine is often prescribed for people who have not been helped with other medications. It has been effective in those people who have tried to commit suicide, hurt themselves or others. There may be a suspicion that the person will try these acts again. It is sometimes referred to as the last resort drug.

Clozapine is classified as an atypical antipsychotic drug. It affects neurochemistry and alters the way the brain functions to improve decision-making and general well-being. It may take several weeks for the full impact of the drug to take effect. The medication should be taken exactly the way the doctor prescribed at the same times every day. Once a sense of well-being is achieved it is important to continue taking the drug. The medication with support and maintain the sense of well-being for as long as it is administered.

Side effects include drowsiness, dizziness, increased salivation, constipation, dry mouth, restlessness and headache. Clozapine can cause a very serious blood disorder. The doctor will take tests before and after drug therapy starts to ensure that the blood disorder does not happen. Any of the following symptoms should be reported immediately: extreme tiredness, weakness, fever, sore throat, chills, or other signs of flu or infection, sores in the mouth or throat.

Clozapine is sold as Clozaril, Azaleptin, Lponex, Fazaclo, Froidir, Denzapine, Zaponex and Clopine.

Source: nlm.nih.gov, Wikipedia, Clozaril.com

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