The Neurobiology of Depression – Depression and the Brain

Major Depressive Disorder: it isn’t just “all in your head.”

I have spent quite a bit of time in the last week looking at a paper: Pathophysiology of Depression: Do We Have Any Solid Evidence of Interest to Clinicians? By Gregor Hasler.

This paper discusses seven research areas relating to the neurobiology of major depressive disorder (MDD). In other words, it talks about the biological evidence of depression, mental illness. It discusses the strengths and weaknesses of biological theories of depression via evidence and aims to point out some of the reasons our current treatment isn’t as successful as it should be. The paper cites 88 other studies and was published in the Journal of World Psychiatry in 2010. It’s pretty educational.


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