
Bupropion ( Amfebutamone, Wellbutrin )
Interactions
|
Name / Class |
Effect of Interaction |
|
Antidepressants ( Tricyclics ):
|
Increase risk of having major seizures |
|
Carbamazepine. |
May increase the effects of Carbamazepine Increase risk of having seizures |
|
Cimetidine. |
May increase bupropion effects |
|
Clozapine. |
Increase risk of having major seizures |
|
Fluoxetine. |
Increase risk of having major seizures |
|
Haloperidol. |
Increase risk of having major seizures |
|
Levodopa. |
May increase the effects of Levodopa Increase risk of having seizures |
|
Lithium. |
Increase risk of having major seizures |
|
Loxapine. |
Increase risk of having major seizures |
|
Molindone. |
Increase risk of having major seizures |
|
Monoamine Oxidase Inhibitors ( MAO ):
|
May increase bupropion levels ( Bupropion Toxicity ) |
|
Phenothiazines:
|
Increase risk of having major seizures |
|
Phenytoin. |
May increase the effects of Phenytoin Increase risk of having seizures |
|
Thioxanthenes:
|
Increase risk of having major seizures |
|
Trazodone. |
Increase risk of having major seizures |
How it works: Increases the levels of norepinphrine and dopamine and is primarily a stimulant to brain activity.

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