Red Wine Could Prevent Depression Related Behavior


According to new research, red grapes and wine could prevent inflammation as well as depression related behaviors.

In the study, researchers found that a natural anti-inflammatory agent called resveratrol existed in the skin of red grapes. The agent blocked the increased inflammation in the brain and prevented depressive behaviors in animals.

“Our research is very relevant to today’s society because it investigates potential treatments for people with an increased susceptibility to depression and related disorders that arise due to social stress,” Susan Wood of the University of South Carolina School of Medicine said.

Rats used in group study

In a previous study, Wood’s team used one rat to bully a group of other rats. Some of the animals developed depressive-like behaviors and inflammation. The bullied rats were given a daily dose of resveratrol equivalent to six glasses of wine. The scientists found that the agent prevented that behavior in the animals who normally exhibited it.

“Resveratrol appears to knock down inflammation throughout the body,” Julie Finnell said. “Certainly, there is a strong case being built now between clinical and preclinical work that inflammation is linked to depressive symptoms, and there is a great need for these findings to be validated in human studies.”

Other studies have shown that resveratrol might be the reason red wine can prevent blood vessel damage and reduce LDL cholesterol. Experiments in animals have suggested that it could also prevent obesity and diabetes.

Wood notes that the group’s findings are exciting because they show that the agent has anti-inflammatory potential in the brain, not just on levels of inflammation in the body.

The researchers are now expanding their study on rats to test whether or not resveratrol can reverse the effects of social stress after they develop.

Source: News Wise / Photo Credit: Flickr


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